Downregulation
Noun
A biological process where a cell decreases the number of receptors or the activity of certain molecules in response to external signals.
The downregulation of insulin receptors can lead to insulin resistance.
Usage tips
Formal
Gene downregulation, Hormonal downregulation, Receptor downregulation
Noun
A biological process where a cell decreases the number of receptors or the activity of certain molecules in response to external signals.
The downregulation of insulin receptors can lead to insulin resistance.
Usage tips
Formal
Gene downregulation, Hormonal downregulation, Receptor downregulation
Definition 1 of 1
Pro Tip 1/3Biological Context
In biology, downregulation often occurs during adaptation to chronic stimulus.
Increased activity of a substance may require the body to downregulate its responses.
Pro Tip 2/3Medical Significance
Understanding downregulation is crucial in pharmacology for optimizing drug dosages.
Medications might unintentionally cause downregulation of receptors, which requires careful monitoring.
Pro Tip 3/3General Usage
In discussions about systems theory, downregulation can signify the reduction of response in complex systems.
Downregulation can also refer to emotional responses in psychology.
Pro Tip 1/3Biological Context
In biology, downregulation often occurs during adaptation to chronic stimulus.
Increased activity of a substance may require the body to downregulate its responses.
Pro Tip 2/3Medical Significance
Understanding downregulation is crucial in pharmacology for optimizing drug dosages.
Medications might unintentionally cause downregulation of receptors, which requires careful monitoring.
Pro Tip 3/3General Usage
In discussions about systems theory, downregulation can signify the reduction of response in complex systems.
Downregulation can also refer to emotional responses in psychology.
Pro Tip 1/3Biological Context
In biology, downregulation often occurs during adaptation to chronic stimulus.
Increased activity of a substance may require the body to downregulate its responses.
Pro Tip 2/3Medical Significance
Understanding downregulation is crucial in pharmacology for optimizing drug dosages.
Medications might unintentionally cause downregulation of receptors, which requires careful monitoring.
Pro Tip 3/3General Usage
In discussions about systems theory, downregulation can signify the reduction of response in complex systems.
Downregulation can also refer to emotional responses in psychology.
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