Use 'how do you do' when you are introduced to someone for the first time as a polite formality.

First Meetings

'How do you do' isn't a question expecting a detailed response, but a polite remark expecting a similar reply.

Not a Question

This phrase is more common in formal or traditional contexts than in casual conversation.

Show sincere interest in someone's wellbeing after an event like illness or a significant life change.

This form of 'how do you do' is suitable when asking about someone's condition after recent changes or events.

The phrase can convey empathy and care, showing that you're emotionally invested in the answer.

When inquiring about someone's job, it politely probes into what their work entails or their feelings about it.

Shows genuine curiosity in how someone is managing or enjoying their career or role.

Best used in a professional setting, possibly during a networking event or job interview.